Items Unsuitable for Generic Prescribing

The following is a list of drugs/preparations which the Area Prescribing Committee would NOT recommend for generic prescribing. For further information refer to the BNF or contact the Pharmacy Department or the Primary Care Medicines Team.  

Generic Name / group Wolverhampton preferred brand  Comments
Adrenaline pens  Emerade®   
Aminophylline     Prescribe by brand name, as there may be differences in the bioavailability of preparations and /or difference between therapeutic and toxic plasma concentrations.  
Buprenorphine 7-day patch  Butec® or Sevodyne® The BNF states that dosage should be reviewed if brand altered.
Buprenorphine 96-hour patch Relevtec® or TranstecTM
Carbamazepine   Prescribe by brand name, as there may be differences in the bioavailability of preparations and /or difference between therapeutic and toxic plasma concentrations
Ciclosporin   Prescribe by brand name, as there may be differences in the bioavailability of preparations and /or difference between therapeutic and toxic plasma concentrations. 
Colecalciferol and calcium chewable tablet 400u/1.5g Primary Care only – Evacal D3® tablet chewable 400u/1.5g  
Colecalciferol and calcium tablet 400u/1.5g Accrete D3® tablet  
Diltiazem   The BNF states that the brand names should be specified as different versions of these modified-release (m/r) preparations may not have the same clinical effect.
Fentanyl 72-hour patch Matrifen® or Mezolar® The BNF states that dosage should be reviewed if brand altered.
Fluticasone propionate 50mcg nasal spray Nasofan®  
Galantamine MR capsule Gatalin XL® or Gazylan XL®  
Ibuprofen gel Fenbid®  
Isosorbide monotrate MR Monomil®  
Lamotrigine   Prescribe by brand name, as there may be differences in the bioavailability of preparations and /or difference between therapeutic and toxic plasma concentrations. 
Levodopa/ carbidopa/ entacapone Stanek® tablets  
Levonorgestrel 1.5mg tablet Upostelle® tablets  
Lithium Priadel® Prescribe by brand name, as there may be differences in the bioavailability of preparations and /or difference between therapeutic and toxic plasma concentrations. 
Macrogol 3350 sachet Cosmocol® or Laxido® sachets  
Mesalazine MR tablet Ocatasa® The BNF states that the brand names should be specified as different versions of these modified-release (m/r) preparations may not have the same clinical effect.
Metformin SR Sukkarto® Prescribe by brand name. Products have different licensed indications.
Morphine   The BNF states that dosage should be reviewed if brand altered.
Nifedipine   The BNF states that the brand names should be specified as different versions of these modified-release (m/r) preparations may not have the same clinical effect.
Oxycodone Shortec® The BNF states that dosage should be reviewed if brand altered.
Oxycodone MR tablet Longtec® MR tablets
Phenytoin   Prescribe by brand name, as there may be differences in the bioavailability of preparations and /or difference between therapeutic and toxic plasma concentrations. 
Quetiapine MR tablet Zaluron XL® tablets or Biquelle XL® tablets  
Ropinirole MR tablet Primary Care only – Ipinnia XL® tablets or Spiroco XL® tablets  
Sodium valproate   Prescribe by brand name, as there may be differences in the bioavailability of preparations and /or difference between therapeutic and toxic plasma concentrations. 
Tacrolimus   The BNF states that the brand names should be specified as different versions of these modified-release (m/r) preparations may not have the same clinical effect.
Theophylline   Prescribe by brand name, as there may be differences in the bioavailability of preparations and /or difference between therapeutic and toxic plasma concentrations. 
Tiotropium inhaler Braltus® Zonda or Spiriva® Respimat Prescribe by brand to ensure consistency of device.
Tolterodine 4mg MR capsule Primary Care only – Neditol XL® or Mariosa XL® capsules  
Tramadol MR tablet Marol®  
Ursodeoxycholic acid 250mg Cholurso®250,g tablets Prescribe by brand name. Brand is contra-indicated in patients who are allergic to peanuts or soya.
Venlafaxine MR capsule Vencarm XL® capsule  
Verapamil   The BNF states that the brand names should be specified as different versions of these modified-release (m/r) preparations may not have the same clinical effect.